MRI Estimation of Global Brain Oxygen Consumption Rate
نویسندگان
چکیده
منابع مشابه
MRI estimation of global brain oxygen consumption rate.
Measuring the global cerebral metabolic rate of oxygen (CMRO(2)) is a valuable tool for assessing brain vitality and function. Measurement of blood oxygen saturation (HbO(2)) and flow in the major cerebral outflow and inflow vessels can provide a global estimate of CMRO(2). We demonstrate a rapid noninvasive method for quantifying CMRO(2) by simultaneously measuring venous oxygen saturation in ...
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The rate of oxygen consumption is a vital marker indicating cellular function during lifetime under normal or metabolically challenged conditions. It is used broadly to study mitochondrial function (Artal-Sanz and Tavernarakis, 2009; Palikaras et al., 2015; Ryu et al., 2016) or investigate factors mediating the switch from oxidative phosphorylation to aerobic glycolysis (Chen et al., 2015; Vand...
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Introduction: Hypercapnia is a common occurrence in pathophysiologic conditions (e.g. cardio-respiratory disease processes) [1]. Carbon dioxide is a potent cerebral vasodilator. Hypercapnia induced hyper-perfusion is often used as a diagnostic tool to measure cerebral vascular reactivity (CVR) to assess the integrity of cerebral circulation which can be altered in pathophysiological states [2]....
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Intuitively, the rate of heat release from an unwanted fire is a major indication of the threat of the fire to life and property. This is indeed true, and a reliable measurement of a fire’s heat release rate was a goal of fire researchers at NBS and other fire laboratories at least as early as the 1960s. Historically, heat release measurements of burning materials were based on the temperature ...
متن کاملEstimation of cerebral metabolic rate of oxygen consumption using combined multiwavelength photoacoustic microscopy and Doppler microultrasound.
The metabolic rate of oxygen consumption is an important metric of tissue oxygen metabolism and is especially critical in the brain, yet few methods are available for measuring it. We use a custom combined photoacoustic-microultrasound system and demonstrate cerebral oxygen consumption estimation in vivo. In particular, the cerebral metabolic rate of oxygen consumption was estimated in a murine...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2010
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.2010.49